I guess many have met with a long wait to open the file selection dialog in 
Gnome , especially if the folder contains several files. For verification, you can run 
zenity --file-selection from the command line and open the “heavy” folder. In the worst case, the dialogue, without downloading the file list, will freeze and hang up the browser with the entered text, which you will have to reprint. At best - wait 1-3 seconds. To correct this situation, you should change the "File Selector" for the browser.
Opera
For 
Opera, this parameter is set on the 
opera: config -> 
Dialog Toolkit page.
- 0 = Autodetect toolkit to use for file selector
 - 1 = Use Qt for file selector
 - 2 = Use GTK for file selector
 - 3 = Use KDE for file selector
 
I suggest choosing Qt as the fastest.
Firefox
For 
Firefox, a simplified dialog is set on the 
about: config page by setting the 
ui.allow_platform_file_picker parameter to 
false . Unfortunately, it is not known how to set Qt directly.
In both cases, a browser reload is not required.