Blood vessels formed in the ears and bones printed on the 3D printer implanted into mice
For several years in medicine they have been using 3D printing to create various human tissues, they print jaws, parts of the skull, vertebrae. The main difficulty is the perception by the human body of alien objects. In the case of the boy, who was replaced by a vertebra , doctors achieved a positive perception thanks to the porous structure.
A similar technique was used at Wake Forest University. They combined bio-in-house inks with micro-channels in the tissues to achieve the formation of blood vessels in the auricle and bones implanted in animals.
It took researchers more than ten years to create the Integrated Tissue and Organ Printing System - ITOP . Biodegradable polymers in the form of a lattice perform the role of an outer framework into which water-based gels containing stem cells are poured. These gels are optimized for cell growth, and micro channels are provided to provide the new organ with oxygen and nutrients.
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Small auricles measuring 3.8 centimeters in size were implanted under the skin of laboratory mice. Two months later, there were signs of vascularization - the formation of blood vessels. That is, the animal organism took new organs for its own.
The same experiment with muscle structures and jaw bone implanted in rats. After five months, vascularization was observed in the bone tissue.
The ITOP itself can use data from CT and MRI examinations of patients to make exact copies of a person’s nose or ear.
A similar technique was used at Wake Forest University. They combined bio-in-house inks with micro-channels in the tissues to achieve the formation of blood vessels in the auricle and bones implanted in animals.
It took researchers more than ten years to create the Integrated Tissue and Organ Printing System - ITOP . Biodegradable polymers in the form of a lattice perform the role of an outer framework into which water-based gels containing stem cells are poured. These gels are optimized for cell growth, and micro channels are provided to provide the new organ with oxygen and nutrients.
')
Small auricles measuring 3.8 centimeters in size were implanted under the skin of laboratory mice. Two months later, there were signs of vascularization - the formation of blood vessels. That is, the animal organism took new organs for its own.
The same experiment with muscle structures and jaw bone implanted in rats. After five months, vascularization was observed in the bone tissue.
The ITOP itself can use data from CT and MRI examinations of patients to make exact copies of a person’s nose or ear.
Source: https://habr.com/ru/post/371829/
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