Polymer nanoparticles will not allow the causative agent of malaria to penetrate into the erythrocytes
A new method to combat the parasite that causes malaria is based on the use of polymer particles to block the receptors for malaria plasmodium, so it cannot interact with the red blood cell and becomes visible to human immunity.
Malaria, formerly called “swamp fever,” is transmitted to humans through mosquito bites from the Anopheles genus and is accompanied by an increase in the size of the spleen, liver, anemia, fever, and chills. According to the World Health Organization, in 2013, about 198 million cases of malaria occurred, about 584 thousand of which ended in death. Prevention measures have reduced mortality by 47% compared with 2000, but this is not enough.
The causative agent of malaria - the parasites of the genus Plasmodia . This parasite lives in red blood cells, which covers it from the immune system, makes it invisible. 48 hours, it is necessary that the infected cell should collapse and a new wave of parasites hit the bloodstream - several cycles of malaria can lead to the death of the carrier. A new method of combating the disease is aimed at interacting with the parasite of polymer nanoparticles: molecules are attached to the particles, to which Plasmodia react, the parasite is connected to such a nanoparticle and can no longer enter the red cell - its receptors are blocked. The parasite becomes visible to the human immune system, which allows it to be destroyed.
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The malaria mosquito serves as a carrier of the causative agent of malaria.
Malaria, formerly called “swamp fever,” is transmitted to humans through mosquito bites from the Anopheles genus and is accompanied by an increase in the size of the spleen, liver, anemia, fever, and chills. According to the World Health Organization, in 2013, about 198 million cases of malaria occurred, about 584 thousand of which ended in death. Prevention measures have reduced mortality by 47% compared with 2000, but this is not enough.
The causative agent of malaria - the parasites of the genus Plasmodia . This parasite lives in red blood cells, which covers it from the immune system, makes it invisible. 48 hours, it is necessary that the infected cell should collapse and a new wave of parasites hit the bloodstream - several cycles of malaria can lead to the death of the carrier. A new method of combating the disease is aimed at interacting with the parasite of polymer nanoparticles: molecules are attached to the particles, to which Plasmodia react, the parasite is connected to such a nanoparticle and can no longer enter the red cell - its receptors are blocked. The parasite becomes visible to the human immune system, which allows it to be destroyed.
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The malaria mosquito serves as a carrier of the causative agent of malaria.
Source: https://habr.com/ru/post/364581/
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