Data recording in E. coli DNA
The fact that DNA is the most effective storage solution is known to all. But when will it be used everywhere? While we are not even thinking about this, we have managed to write data to the genome of E. coli at MIT.
In 2012, Harvard bioengineers were able to write about 700 terabytes of data in DNA. It was a DNA chip: DNA fragments were printed using an inkjet printer on a glass substrate. Scientists recorded books on genetics on a chip, then transferred them back to digital format and got only two errors out of a million bits.
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This time we are talking about living cells. Several analog data streams were recorded on a special device using a population of bacterial cells. It’s like a “tape cassette recorder with DNA,” as one of the developers calls it. Data can be written, erased and rewritten.
Moreover, the information recorded in their DNA is inherited!
This recorder is called SCRIBE , Synthetic Cellular Recorders Integrating Biological Events. Single DNA strands are integrated into the genetic base of the cell. Having added light-sensitive proteins to the genetic chain, the researchers simply “turned on the recorder” with the help of light. Decoding information allows you to learn about events that occurred with cells - for example, how long they were exposed to a chemical substance.
In 2012, Harvard bioengineers were able to write about 700 terabytes of data in DNA. It was a DNA chip: DNA fragments were printed using an inkjet printer on a glass substrate. Scientists recorded books on genetics on a chip, then transferred them back to digital format and got only two errors out of a million bits.
')
This time we are talking about living cells. Several analog data streams were recorded on a special device using a population of bacterial cells. It’s like a “tape cassette recorder with DNA,” as one of the developers calls it. Data can be written, erased and rewritten.
Moreover, the information recorded in their DNA is inherited!
This recorder is called SCRIBE , Synthetic Cellular Recorders Integrating Biological Events. Single DNA strands are integrated into the genetic base of the cell. Having added light-sensitive proteins to the genetic chain, the researchers simply “turned on the recorder” with the help of light. Decoding information allows you to learn about events that occurred with cells - for example, how long they were exposed to a chemical substance.
Source: https://habr.com/ru/post/363177/
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