Based on the general statistics on mobile and desktop browsers, IE use almost 15% of users:

Exit Windows 10 announced at the end of the summer. As an embedded browser, Windows 10
will use Microsoft Edge . Among other things, the new browser from Microsoft
will support the Windows Audio API . Therefore, in about a year, an HTML5 application using the Windows Audio API will run in any browser on any platform.
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So to say, the slogan “It is written once works everywhere,” but in reality, and not only in theory.
Many manufacturers of online
DAW are already
working on translating their applications from Adobe Flash to HTML5.
Interface Editor from Swedish Soundation:

Probably in the near future we should expect the emergence of new projects in the field of online work with sound.
We decided to help the programmers of near-music software and release the wavetable synthesizer used in
our service under a free license.
With the help of our synthesizer, you can do about
these applications:

The project will be built into Babylon.js free WebGL framework. You can learn about the integration process on the
official Babylon.js forum .