Harvard scientists have learned to grow insulin producing cells on an industrial scale.
The cure of diabetes mellitus of the first type can be on the way thanks to the open-door scientists from Harvard University to grow insulin-producing cells from stem cells in quantities necessary for transplantation into the human pancreas.
Two weeks after transplantation later: beta cells from human stem cells form islet clusters and produce insulin, curing experimental mice
This is the result of Harvard professor Douglas Melton, twenty-three years old, who has been searching for a cure since his son Sam was diagnosed with type 1 diabetes .
Insulin-producing beta cells derived from stem cells are now being tested in animals, including primates. According to the professor, they still produce insulin several months after transplantation.
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An illustration from Cell magazine
Type 1 diabetes is an autoimmune disease in which the beta cells of the pancreas stop producing the hormone insulin that regulates blood glucose. Elevated blood glucose causes great damage to the organs of the body. If the Melton cell transplantation works, it can save millions of people from the need for daily insulin shots and the risks involved . “We are now in one preclinical step from the finish,” says Professor Melton. Answering the question about his son’s reaction, he said: “I think, like all children, he assumed that if the father said he would do it, he would this".
Douglas Melton
Diabetes of the first type affects only about 10% of patients with diabetes, but this is the most common type of diabetes among children.
In the commentary to the Telegraph newspaper , Chris Manson, a professor at the University College London, called this discovery possible one of the key medical breakthroughs: time antibiotics - in the fight against bacterial infections. "
Professor of the New York University of Rockefeller University Elayne Fuchs described this opening as “it is one of the most important achievements in the field of stem cells today. For decades, scientists have been looking for an opportunity to produce pancreatic beta cells suitable for transplantation and subsequent insulin production. ”
An article on development published in the journal Cell .
a source
via
[ inform andorro news ]
Two weeks after transplantation later: beta cells from human stem cells form islet clusters and produce insulin, curing experimental mice
This is the result of Harvard professor Douglas Melton, twenty-three years old, who has been searching for a cure since his son Sam was diagnosed with type 1 diabetes .
Insulin-producing beta cells derived from stem cells are now being tested in animals, including primates. According to the professor, they still produce insulin several months after transplantation.
')
An illustration from Cell magazine
Type 1 diabetes is an autoimmune disease in which the beta cells of the pancreas stop producing the hormone insulin that regulates blood glucose. Elevated blood glucose causes great damage to the organs of the body. If the Melton cell transplantation works, it can save millions of people from the need for daily insulin shots and the risks involved . “We are now in one preclinical step from the finish,” says Professor Melton. Answering the question about his son’s reaction, he said: “I think, like all children, he assumed that if the father said he would do it, he would this".
Douglas Melton
Diabetes of the first type affects only about 10% of patients with diabetes, but this is the most common type of diabetes among children.
In the commentary to the Telegraph newspaper , Chris Manson, a professor at the University College London, called this discovery possible one of the key medical breakthroughs: time antibiotics - in the fight against bacterial infections. "
Professor of the New York University of Rockefeller University Elayne Fuchs described this opening as “it is one of the most important achievements in the field of stem cells today. For decades, scientists have been looking for an opportunity to produce pancreatic beta cells suitable for transplantation and subsequent insulin production. ”
An article on development published in the journal Cell .
a source
via
[ inform andorro news ]
Source: https://habr.com/ru/post/240087/
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